动物昼夜节律相关miRNAs研究进展

葛莹,狄冉,储明星*,刘秋月,胡文萍,王翔宇

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家畜生态学报 ›› 2014, Vol. 35 ›› Issue (12) : 1-5.
学科动态

动物昼夜节律相关miRNAs研究进展

  • 葛莹,狄冉,储明星*,刘秋月,胡文萍,王翔宇
作者信息 +

Advances on miRNAs Related to Circadian Rhythm of Animals

  • GE Ying, DI Ran, CHU Mingxing*, LIU Qiuyue, HU Wenping, WANG Xiangyu
Author information +
History +

摘要

microRNAs(miRNAs)是一类长度为21~24nt的非编码小RNA,通过与靶mRNAs的3′UTR结合在转录后水平上沉默基因表达,参与多种生理、生化、病理过程。目前有许多研究表明miRNAs影响动物的昼夜节律。论文就miRNAs在昼夜节律中的调控机制进行综述,揭示其在昼夜节律系统中的重要作用,为更深入理解动物昼夜节律系统提供理论参考和研究思路。

Abstract

microRNAs (miRNAs) are 21to 24nucleotidelong noncoding RNAs and silence gene expression in posttranscriptional level by binding to the 3′untranslated regions (UTRs) of target mRNAs in physiological,biochemical and pathological processes. Many recent research indicated that miRNAs affected circadian rhythm of animals. This review aimed to summarize the regulatory mechanism of miRNAs in circadian rhythm and their important roles in circadian system, so as to provide basis and information in detecting animal circadian rhythm.

关键词

miRNAs / 昼夜节律 / 钟控基因

Key words

RNAs / circadian rhythm / clockcontrolled genes

引用本文

导出引用
葛莹,狄冉,储明星*,刘秋月,胡文萍,王翔宇. 动物昼夜节律相关miRNAs研究进展. 家畜生态学报. 2014, 35(12): 1-5
GE Ying, DI Ran, CHU Mingxing*, LIU Qiuyue, HU Wenping, WANG Xiangyu. Advances on miRNAs Related to Circadian Rhythm of Animals. Journal Of Domestic Animal Ecology. 2014, 35(12): 1-5

基金

国家自然科学基金项目(No.31472078、No.31101687和No.31402041);北京市自然科学基金项目(No.6144029);中国农业科学院科技创新工程(No.ASTIPIAS13);国家肉羊产业技术体系专项(No.CARS-39);中央级公益性科研院所基本科研业务费专项(No.2011cj-7和No.2013ywf-zd-1

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