天蚕素抗菌肽对断奶仔猪生长性能和猪瘟及伪狂犬抗体水平的影响

蒋桂韬,杨 俊,邱美珍,张 旭,戴求仲

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家畜生态学报 ›› 2013, Vol. 34 ›› Issue (3) : 25-29.
科学研究

天蚕素抗菌肽对断奶仔猪生长性能和猪瘟及伪狂犬抗体水平的影响

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Effects of Antibacterial Peptide Cecropins on Growth Performance and Antibody Level of CSFV and PRV in Weaned Piglets

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摘要

为探明断奶仔猪饲粮中添加天蚕素抗菌肽替代吉他霉素对断奶仔猪生长性能、腹泻和猪瘟及伪狂犬病抗体的影响。选择杜×大×长三元断奶仔猪120头,随机分为2个处理,每处理6个重复,每重复10头猪。对照组饲粮为基础饲粮中添加50%吉他霉素140 mg/kg和10%硫酸粘杆菌素540 mg/kg,试验组饲粮为对照饲粮用天蚕素抗菌肽(预混料专用型)160 mg/kg替代吉他霉素。试验期为44 d。结果表明:试验组仔猪平均日增重比对照组提高了4.94%(P>0.05),而料重比和腹泻率比对照组分别降低了5.13%(P<0.05)和18.66%(P>0.05);试验组仔猪血清中猪瘟抗体阻断率、阳性率和合格率分别比对照组高出117.53%(P<0.05)、499.88%和30%,而2组间猪伪狂犬病抗体水平没有差异(P>0.05);试验组仔猪每kg增重饲料成本比对照组降低了0.38元。由此可见,天蚕素抗菌肽替代吉他霉素与硫酸粘杆菌素配伍使用可提高断奶仔猪饲料转化率、猪瘟抗体水平和经济效益。

Abstract

The experiment was conducted to evaluate the effects of antimicrobial peptide cecropins instead of kitasamycin on growth performance, diarrhea incidence, and antibody level of Classical swine fever (CSFV) and Porcine pseudorabies virus (PRV) in weaned piglets. One hundred and twenty weaned piglets of Duroc×Landrace×Yurkshire were randomly allocated to 2 groups with 6 replicates of 10 pigs each. The experiment group was fed basal diet supplemented with a combination of 160 mg/kg antimicrobial peptide cecropins and 540 mg/kg 10% colistin, while the control group was fed basal diet supplemented with a combination of 140 mg/kg 50% kitasamycin and 540 mg/kg 10% colistin. The experiment lasted for 44 days. The results showed that compared to the control group, ADG in the experiment group were improved by 4.94% (P>0.05). F/G and diarrhea incidence in the experiment group were lower than that in the control group, and respectively reduced by 5.13% (P<0.05) and 18.66% (P>0.05). Blocking rate, positive rate and qualified rate of CSFV antibody in the experiment group were higher than that in control group, and improved by 117.53% (P<0.05),499.88% and 30% respectively, whereas PRV antibody levels were not significantly different (P>0.05) between 2 groups. Compared with the control group, the feed cost of nursery piglets in the experiment group reduced by 0.38 Yuan per kg body weight gain. It was concluded that diet supplemented with a combination of 160 mg/kg antimicrobial peptide cecropins and 540 mg/kg 10% colistin have special ascendancy in raise feed ratio, antibody level to CSFV and economic benefits in weaned piglets.

关键词

天蚕素抗菌肽 / 吉他霉素 / 断奶仔猪 / 生长性能 / 猪瘟抗体 / 猪伪狂犬抗体

Key words

antimicrobial peptide cecropins / kitasamycin / weaned piglets / growth performance / classical swine fever antibody / porcine pseudorabies virus antibody

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蒋桂韬,杨 俊,邱美珍,张 旭,戴求仲. 天蚕素抗菌肽对断奶仔猪生长性能和猪瘟及伪狂犬抗体水平的影响. 家畜生态学报. 2013, 34(3): 25-29
JIANG Gui-tao, YANG Jun, Qiu Mei-zhen, ZHANG Xu, DAI Qiu-zhong. Effects of Antibacterial Peptide Cecropins on Growth Performance and Antibody Level of CSFV and PRV in Weaned Piglets. Journal Of Domestic Animal Ecology. 2013, 34(3): 25-29

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