Polymorphism of ESRRα Gene and Its Association with Meat Quality in Qinchuan Cattle

ZHANG Si-hui,MA Shen, ZHENG Jie,CHANG Xin-yue,ZHOU Guang-xian,CAO Bao-hong,ZHANG En-ping

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Journal Of Domestic Animal Ecology ›› 2012, Vol. 33 ›› Issue (4) : 9-12.

Polymorphism of ESRRα Gene and Its Association with Meat Quality in Qinchuan Cattle

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Abstract

Estrogen-related receptors α (ESRRα) is a multifunctional protein which is involved in differentiation of preadipocytes to adipocytes and body energy metabolism. It's an important candidate gene for meat quality selection through markerassisted selection (MAS). In this study, based on the PCR-RFLP technology,one single nucleotide polymorphism (SNP) (C147A in inxon 1) of the ESRRα gene was discovered. The analysis result showed that there were 2 alleles (A and C) and 3 genotypes(AA,CA and CC) in 282 Qinchuan Cattle.The frequences of alleles found was 0.4025 for A and 0.5975 for C. The frequences of genotypes found was 0.1844 for AA,0.4363 for CA and 0.3794 for CC.The association between genotype markers and meat traits were analyzed by general linear model at the level of DNA. The result was the CC genotype of Qinchuan CattleESRRα gene showed a highly significant negative effection Marbling (MB )traits (P< 0.05 ) ,and animals with the CC genotype have a significantly lower Backfat thickness (BFT) compared to the CA and AA genotypes (P<0.01).

Key words

Qinchuan cattle / ESRR&alpha / gene / SNP / meat quality traits

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ZHANG Si-hui,MA Shen, ZHENG Jie,CHANG Xin-yue,ZHOU Guang-xian,CAO Bao-hong,ZHANG En-ping. Polymorphism of ESRRα Gene and Its Association with Meat Quality in Qinchuan Cattle. Journal Of Domestic Animal Ecology. 2012, 33(4): 9-12

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