［1］林学颜, 张   玲. 现代细胞与分子免疫学［M］. 北京: 科学出版社, 2000: 2-4.

［2］王世若, 王兴龙, 韩文瑜. 现代动物免疫学［M］. 长春: 吉林科学技术出版社, 2001: 1-15.

［3］孙振钧.蚯蚓活性蛋白研究［D］.北京: 中国农业大学, 1997.

［4］杨廷彬, 尹学念. 实用免疫学［M］. 长春: 长春出版社, 1994:117.

［5］刘凌云, 郑光美. 普通动物学［M］. 北京: 高等教育出版社, 1997: 187.

［6］Bruke J M. An ultrastructural analysis of the cuticle, epidermis and esophageal epithelium of Eisenia fotida (Oligochaeta)［J］. J Morph, 1974, 142: 301-320.

［7］Anderson W A, Weissman A, Eills R A. Cytodifferentiation during sperm iogenesis in Lumbricus terrestris［J］. J Cell Biol, 1976, 32:11-26.

［8］Jamieson B G M. The ultrastructure of the Oligochaeta［M］. London: Academic Press, 1981:1-44.

［9］肖亿群, 陆雅君, 邱江平. 白颈环毛蚓皮肤的超微结构［J］. 上海师范大学学报∶自然科学版, 2002, 31（2）：79-86.

［10］Singeton L. The chemical structure of earthworm cuticle［J］. Biochem Biophysica Acta, 1957, 24: 67-72.

［11］Fischer E, Horvath I. Cytochemical studies on the cuticle and epiderm is of tubifex Müll  with special regard to the location of pdysaccharides, heavy metals and the DAB-reactivity［J］. Histochemistry and Cell Biology, 1977, 54: 259-271.

［12］王   冲, 孙振钧, 郑冬梅, 等. 大肠杆菌对赤子爱胜蚓体表超微结构的影响［J］. 应用与环境生物学报, 2007, 13(2):215-219.

［13］许智芳. 蚯蚓的结构与功能［M］. 北京: 科学出版社, 1986: 20-30. 

［14］张宝贵. 蚯蚓与微生物的相互作用［M］. 生态学报, 1997, 17(5): 556-560.

［15］Pedersen J C, Hendriksen N B. Effect of passage through the intestinal tract of detritivore earthworms (Lumbricusspp.) on the number of selected Gram-negative and total bacteria［J］. Biol Fertil Soils, 1993, 16: 227-232.

［16］张立宏,许光辉. 微生物和蚯蚓协同作用对土壤肥力影响的研究［J］. 生态学报, 1990, 10(2): 116-120.

［17］Dash M C, Mishra P C, Behera N. Fungal feeding by tropical earthworm［J］. Trop Ecol, 1979, 20: 9-12. 

［18］Parle J N. A microbiological study of earthworm casts［J］. J Gener Microbiol,1963, 31: 13-22.

［19］王   冲, 郑冬梅, 冀峻玲, 等. 蚯蚓脂肪及其在抗菌物理屏障中的作用［J］. 农业环境科学学报, 2005, 24(4):732-736.

［20］Bilej M, Brys L, Beschin A, et al. Identification of a cytolytic protein in the coelomic fluid of Eisenia foetida earthworms［J］. Immunol Lett, 1995, 45: 123.

［21］Valembois P. Etude ultrastructurale des coelomocytes du lombricien Eisenia fetida (Sav)［J］. Bull Soc Zool Fr, 1971, 96: 59-72.

［22］李兴杰. 免疫系统在动物系统发育过程中的发生和发展［J］. 唐山师范学院学报, 2001, 23(2): 62-63.

［23］Stein E A, Avtalion R R, Cooper E L. The coelomocytes of the earthworm Lumbricus terrestris: morphology and phagocytic properties［J］. J Morphol, 1977, 153: 467.

［24］Dales R P, Kalac Y. Phagocytic defense by the earthworm Eisenia foetida against certain pathogenic bacteria［J］. Comp Biochem Physiol, 1992, 101: 487.

［25］Valembois P, Lassegues M. In vitro generation of reactive oxygen species by free coelomic cells of the annelid Eisenia fetida andrei: an analysis by chemiluminescence and nitro blue tetrazolium reduction［J］. Dev Comp Immunol, 1995, 19: 195-204. 

［26］Valembois P, Lassegues M, Roch P. Formation of brown bodies in the coelomic cavity of the earthworm Eisenia fetida andrei and attendant changes in shape and adhesive capacity of constitutive cells［J］. Dev Comp Immunol, 1992, 16: 95.

［27］Stein E A, Wodjani A, Cooper E L. Agglutinins in the earthworm, Lumbricus terrestris: naturally occurring or induced ［J］. Dev Comp Immunol, 1982, 6: 407.

［28］Stein E A, Younai S, Cooper E L. Bacterial agglutinins of the earthworm, Lumbricus terrestris［J］. Comp Biochem Physiol B, 1986, 84: 409. 

［29］Stein E A, Younai S, Cooper E L. Separation and partial purification of agglutinins from coelomic fluid of the earthworm, Lumbricus terrestris［J］. Comp Biochem Physiol B, 1990, 97: 701.

［30］Stein E A, Cooper E L. Carbohydrate and glycoproteins inhibitors of naturally occurring and induced agglutinins in the earthwom, Lumbricus terrestris［J］. Comp Biochem Physiol B, 1983, 76: 197.

［31］Beschin A, Bilej M, Hanssens F, et al. Identification and cloning of a glucan and lipopolysaccharide-binding protein from Eisenia fetida earthworm involved in the activation of prophenoloxidase casecade［J］. J Biol Chem, 1998, 273(38): 24 948-24 954.

［32］Shike H, Lauth X, Westerman M E. Bass hepcidin is a noval antimicrobial peptide induced by bacterial challenge［J］. Eur J Biochem, 2002, 269: 2 232-2 237.

［33］Tomasinsig L, Scocchi M, Di Loreto C. Inducible expression of an antimicrobial peptide of the innate immunity in polymorphonuclear leukocytes［J］. J Leukoc Biol, 2002, 72:1 003-1 010.

［34］Cho J H, Park C B, Yoon Y G, et al. Lumbricin I, a novel proline-rich antimicrobial peptide from the earthworm: purification, cDNA cloning and molecular characterization［J］. Biochim Biophys Acta, 1998, 1408:67-76. 

［35］陈   飞, 刘艳玲. 蚯蚓有效成分研究进展［J］. 微生物学杂志, 2000, 20(1):45-46.

［36］崔东波, 郑彦杰, 王运吉, 等. 蚯蚓抗菌肽的分离［J］. 大连轻工业学院学报, 2004, 23(4):265-269.

［37］孙振钧. 蚯蚓抗菌肽研究进展［C］//2010年家畜环境与生态学术研讨会论文集, 2010: 533-539.

［38］王   庄, 李曾夏子, 李文平, 等. 蚯蚓中3~30 kD抗菌肽的分离及抗菌效果研究［J］. 湖南农业大学学报∶自然科学版,2010, 36(1): 50-53.

［39］张希春, 孙振钧, 高   锦, 等. 蚯蚓抗菌肽EABP1的分离纯化及部分性质［J］. 应用与环境生物学报, 2003, 9(1): 36-38.

［40］Alexandra M, Marguerite L. Purification, characterization and activities of two hemolytic and antibacterial protein from coelomic fluid of the annelid Eisenia fetida Andrei［J］. Biochim Biophys Acta, 1997, 1337(1):123-132.

［41］Lassegues M, Milochau A, Doignon F, et al. Sequence and expresdsion of an Eisenia fetidaderived cDNA clonr that encodes the 40 kDa fetidin antibacterial protein［J］. Eur J Biochem,1997, 678: 1.

［42］Dhainaut A, Raveillon B, Beri M, et al. Purification of an antibacterial protein in the coelomic fluid of Nereis diversicolor (Annelida Polychaeta): similitude with a cadmiumbinding protein［J］. Comp Biochem Physiol C, 1989, 94: 555-560.

［43］Dhainaut-Courtois N, Nejmeddine A, Baert J L, et al. Localisation immunocytochimique d'une proteine complexant le cadmium chez un ver marin (Nereis diversicolor)［J］. C R Acad Sci Paris, 1987, 305: 237-241.

［44］张希春, 孙振钧, 禚如朋, 等. 蚯蚓两种抗菌肽的分离纯化及部分性质［J］.生物化学与生物物理进展, 2002, 29(6): 955-961.

［45］刘艳琴. 蚯蚓（Eisenia fetida）组分体外抗病毒、抗肿瘤作用和抗菌寡肽的分离纯化及部分特性［D］. 北京:中国农业大学, 2003.

［46］Laulan A, Morel A, Lestage J, et al. Evidence of synthesis by Lumbricus terrestris of specific substances in response to an immunization with a synthetic hapten［J］. Immunology, 1985, 56: 751.

［47］Tuckova L, Rejnek J, Bilej M, et al. Characterization of antigen-binding protein in earthworms Lumbricus terrestris and Eisenia fetida［J］. Dev Comp Immunol, 1991, 15: 263.［48］Tuckova L, Rejnek J, Sima P. Response to parent stimulation in earthworm Lumbricus terrestris and Eisenia foetida［J］. Dev Comp Immunol, 1988, 12: 287.

［49］Bilej M, Tuckova L, Romanovsky A. Characterization of the limited specificity of antigen recognition in earthworms［J］. Folia Microbiol, 1995, 40: 436.

［50］Lassalle F, Lassegues M, Roch P. Protein analysis of eathworm coelomic fluid. IV. Evidence, activity induction and purification of Eisenia fetida andrei lysozyme (Annelida) ［J］. Comp Biochem Physiol B, 1988, 91:187.

［51］Hirigoyenberry F, Lassalle F, Lassegues M. Antibacterial activity of Eisinia fetida andrei coelomic fluid: transcription and translation regulation of lysozyme and proteins evidenced after bacterial infestation［J］. Comp Biochem Physiol, 1990, 95: 7175.

［52］Milochau A, Lassegues M, Valembois P. Purification, characterization and activities of two hemolytic and antibacterial proteins from coelomic fluid of the annelid Eisenia fetida andrei［J］. Biochem Biophys Acta, 1997, 1337: 123.

［53］耿   晖. 地龙药理研究概况［J］. 时珍国医国药, 2000, 11(10):952.